SIDE EFFECTS: Hot flashes, sweating, or leg cramps may occur. If these effects persist or worsen, notify your doctor or pharmacist promptly. Raloxifene (Evista) may infrequently cause serious blood clots to form in the legs, lungs, or eyes. Tell your doctor immediately if any of these unlikely but serious side effects occur: leg swelling/pain, trouble breathing, chest pain, vision changes. If you notice other effects not listed above, contact your doctor or pharmacist.
PRECAUTIONS: Before taking raloxifene, tell your doctor or pharmacist if you are allergic to it, or if you have any other allergies. This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: active or past history of blood clots (e.g., deep venous thrombosis, pulmonary embolism, retinal vein thrombosis). Lack of movement may increase the risk for blood clots. Your doctor will instruct you to stop taking this medication at least 3 days before surgery or during long periods of inactivity (e.g., bedrest). Do not start taking raloxifene until you are routinely and actively moving again. During long periods of travel, walk or move periodically to keep the blood flowing through your body. Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, congestive heart failure, cancer, high blood cholesterol levels, history of high blood fat (triglyceride) levels due to estrogen treatment. This medication must not be used during pregnancy because it may cause fetal harm. If you become pregnant or think you may be pregnant, inform your doctor immediately. It is not known whether this drug passes into breast milk. Breast-feeding while using this medication is not recommended. Consult your doctor before breast-feeding.
DRUG INTERACTIONS: This drug should not be used with the following medication because very serious interactions may occur: cholestyramine (or other anion-exchange resins). If you are currently using this medication, tell your doctor or pharmacist before starting raloxifene. Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: diazepam, diazoxide, estrogens, lidocaine, warfarin. This product can affect the results of certain lab tests. Make sure laboratory personnel and your doctors know you use this drug. Do not start or stop any medicine without doctor or pharmacist approval.
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