Prednisolone is used to treat many different conditions such as allergic disorders, skin conditions, ulcerative colitis, arthritis, lupus, psoriasis, or breathing disorders.
You should not use this medication if you are allergic to prednisolone, or if you have a fungal infection anywhere in your body.
Before taking prednisolone, tell your doctor about all of your medical conditions, and about all other medicines you are using. There are many other diseases that can be affected by steroid use, and many other medicines that can interact with steroids.
Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.
Prednisolone side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Prednisolone Dosing Information
Usual Adult Dose for Multiple Sclerosis:
Tablets and syrup for acute exacerbations: 200 mg daily for one week followed by 80 mg every other day for 1 month.
Usual Adult Dose for Anti-inflammatory:
Sodium phosphate: Oral: 5 to 60 mg per day in divided doses 1 to 4 times/day.
Intravenous or Intramuscular: 4 to 60 mg/day
Usual Pediatric Dose for Immunosuppression:
Oral: 0.1 to 2 mg/kg/day in divided doses 1 to 4 times a day.
Intravenous: 0.1 to 2 mg/kg/day in divided doses 1 to 4 times a day.
Usual Pediatric Dose for Asthma -- Acute:
Oral: 1 to 2 mg/kg/day in divided doses 1 to 2 times a day for 3 to 5 days.
Intravenous: 2 to 4 mg/kg/day divided 3 or 4 times a day.
Usual Pediatric Dose for Nephrotic Syndrome:
First 3 episodes: Initial dose: 2 mg/kg/day (maximum dose 80 mg/day) until urine is free of protein for 3 consecutive days (maximum: 28 days); followed by 1 to 1.5 mg/kg/dose every other day for 4 weeks.
Frequent relapses or long-term maintenance dose: 0.5 to 1 mg/kg/dose given every other day for 3 to 6 months.
What other drugs will affect prednisolone?
There are many other medicines that can interact with steroids. Below is only a partial list of these medicines:
- aspirin (taken on a daily basis or at high doses);
- a diuretic (water pill);
- a blood thinner such as warfarin (Coumadin);
- cyclosporine (Gengraf, Neoral, Sandimmune);
- insulin or diabetes medications you take by mouth;
- ketoconazole (Nizoral);
- rifampin (Rifadin, Rifater, Rifamate, Rimactane); or seizure medications such as phenytoin (Dilantin) or phenobarbital (Luminal, Solfoton).
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